DM18 Science starts with peer-reviewed clinical literature — not trends, not marketing claims. Every ingredient, every dose backed by published research — nutraceutical science applied to daily metabolic health.
Each DM18 Science product targets a distinct metabolic pathway, formulated from compounds with the strongest published evidence base.
Berberine HCl (500mg), Alpha-Lipoic Acid (300mg), and Chromium Picolinate (200mcg). Three compounds with documented effects on glucose metabolism and insulin sensitivity in clinical literature.
Kaneka Ubiquinol™ (200mg) — the active, reduced form of CoQ10 with superior bioavailability versus standard ubiquinone. Supports mitochondrial energy production in cardiac and metabolic cells.
A focused two-compound formula combining Berberine (500mg twice daily) with Chromium Picolinate (200mcg). Streamlined for those who want targeted metabolic support without additional compounds.
No reverse-engineering from competing products. No trend-chasing. Every DM18 formula follows the same systematic research protocol.
We search PubMed and Cochrane for randomized controlled trials studying the metabolic pathway we're targeting. Only compounds with multiple published RCTs advance.
Each ingredient is dosed to match the range used in the studies showing efficacy — not the lowest viable dose for cost efficiency.
Compounds are evaluated for known interactions and synergies. We avoid ingredient combinations where the evidence for interaction is unclear.
Produced in GMP-certified facilities. Every batch undergoes third-party testing for identity, purity, and potency before release.
A snapshot of the published clinical data that drives our formulation decisions.
Multiple RCTs demonstrate that berberine (500mg 3× daily) shows significant reductions in fasting glucose and HbA1c in published clinical studies involving type 2 diabetic subjects.
ALA (300–600mg daily) has been studied for its role as a universal antioxidant and its capacity to enhance glucose uptake via AMPK activation in muscle tissue.
Chromium picolinate (200mcg daily) has been shown in meta-analyses to modestly improve insulin receptor sensitivity, particularly in subjects with suboptimal chromium status.
Ubiquinol (the reduced form of CoQ10) is the active participant in the mitochondrial electron transport chain. Studies show superior plasma absorption versus standard ubiquinone.
Magnesium is a required cofactor for over 300 enzymatic reactions. Glycinate chelation provides superior GI tolerance and absorption versus oxide or citrate forms.
D3 and K2 (MK-7 form) work synergistically — D3 increases calcium absorption while K2 directs calcium to bone rather than arterial tissue, per published cardiovascular research.
We apply pharmaceutical manufacturing and testing standards to dietary supplement formulations.
Produced in FDA-registered, GMP-certified facilities with batch documentation at every production stage.
Independent laboratory verification of identity, potency, purity, and microbiological safety for every batch.
No proprietary blends. Every active ingredient listed with exact amounts matching clinical dosage protocols.
Certificates of Analysis from third-party labs available to any customer upon request for any purchased product.
Receive summaries of new metabolic research and early access to upcoming DM18 Science formulas.
